Boston University

Humboldt-Universität
zu Berlin


Boston, MA
July 24 - 27, 2002

 

 

       

 

Local Organizers
Prof. Zhiping Weng
Prof. Rosina Georgiadis
Prof. Lev Levitin
Karl Clodfelter

Steering Committee
Prof. Charles DeLisi
Chair, Bioinformatics Graduate Program
Boston University

Prof. Tom Tullius
Chair, Chemistry Department,
Boston University

Prof. Dr. Reinhart H. Heinrich
Research Group Leader, Department of Theoretical Biophysics

Berlin Organizers
Prof. Dr. Ernst W. Knapp
Prof. Dr. Hermann G. Holzhutter
Prof. Erwin Frey

 
Boston University and Humboldt University are hosting an annual bioinformatics workshop at Boston University in the summer 2002.
     
Sponsored By:
Boston University Bioinformatics Program: Boston, MA, USA
Humboldt University Program and Evolution of Cellular & Marcomolecular Processes: Berlin, Germany


All Scheduled Events Will Be Held in or Directly Outside of Photonics Rm.206


Schedule of Events

Wednesday, July 24, 2002

9:15am Professor David Campbell, Dean, College of Engineering, Boston University

Introduction by Prof. Charles DeLisi
9:40am Prof. Charles DeLisi
Chair, Bioinformatics Graduate Program
Dean Emeritus, College of Engineering, Boston University
10:00am Professor Dr. Reinhart Heinrich
Humboldt University, Institute of Biology,
Research Group Leader, Department of Theoretical Biophysics
MACROMOLECULAR RECOGNITION AND MODELING
Introductions by Professor Rosina Georgiadis
10:20am Professor Evan Evans
Boston University Biomedical Engineering & Physics Departments
"Dynamic Force Chromatography: high-resolution assay of weak biomolecular interactions"
10:55am Coffee Break
11:15am Björn Peters
Humboldt University, Faculty of Medicine (Charité),
Institute of Biochemistry
"Sequence based prediction of peptide binding ability to MHC class I"
11:45am Jahnavi Prasad
Boston University, Bioinformatics Graduate Program
"Confident Comparative Modeling Based on Consensus Alignment"
12:15pm Lunch Break
1:45pm Professor Dr. Hermann-Georg Holzhutter
Humboldt University, Faculty of Medicine (Charité),
Institute of Biochemistry
"Proteolytic peptides generated by proteasomes: how many?"
2:20pm Julian Mintseris
Boston University, Bioinformatics Graduate Program
"Contacts in Protein-protein Recognition"
2:50pm Coffee Break
3:10pm Vio Buchete
Boston University, Chemistry Department
"Spherical Harmonic Analysis of Orientation Dependent Statistical Potentials Derived from Protein Structural Databases"
3:40pm Enoch Huang, Ph.D.
Adjunct Assistant Professor, Bioinformatics Program,
Boston University
Head of Molecular Informatics, Pfizer Discovery Technology Center
"Sequence, Structure, and Function in the GPCR superfamily"

Thursday July 25, 2002

MACROMOLECULAR RECOGNITION AND MODELING
Introductions by Karl Clodfelter, Boston University

9:00am Professor Sandor Vajda
Boston University, Biomedical Engineering Department
"Computational solvent mapping for the analysis of enzyme active sites"
9:35am Professor Dr. Earnst Walter Knapp
Free University of Berlin, Department of Biology, Chemistry, and Pharmacy
"Synthetic Cytochrome b: Computer Modeling and Evaluation of Redox Potentials"
10:10am Yu Zheng
Boston University, Bioinformatics Graduate Program
"Genomics annotation using co-evolution profiles of gene clusters"
10:40am Coffee Break
11:00am Rong Chen
Boston University, Bioinformatics Graduate Program
"A Novel Shape Complementarity Scoring Function for Protein Docking"
11:30am Carlos Camacho
Research Assistant Professor
Boston University, Biomedical Engineering Dept.
"On the origin and conservation of singlets and paralogs across genomes"
12:05pm Lunch Break
1:30pm Poster Session

Friday July 26, 2002

GENOME ANNOTATION
Introductions by Prof. Zhiping Weng, Boston University
9:00am Key Note Speaker
George Church, Ph.D.
Professor of Genetics, Harvard Medical School
Director of the Lipper Center for Computational Genetics
"Biosystems Measures and Models of Reproductive Fitness"
Introduction by Professor Zhiping Weng
9:45am Professor Scott Mohr
Boston University, Dept. of Chemistry
Biomolecular Engineering Research Center
"Examination of Eukaryotic Origins via Sequence/Structure Correlations of Small-subunit Ribosomal Proteins"
10:20am Coffee Break
10:40am Megon Walker
Boston University, Bioinformatics Graduate Program
"Prokaryotic translation initiation site detection by product hidden Markov model"
11:10am Research Asst. Prof. Joel Graber
Boston University, Bioinformatics Program
Bioinformatic studies of post-transcriptional processes
11:45am Lunch Break
PATHWAY IDENTIFICATION AND ANALYSIS
Introductions by Joel Graber, Research Assistant Professor, Boston University
1:50pm Dr. Jana Wolf
Humboldt University, Institute of Biology,
Department for Theoretical Biology
"RAS-mediated signal transduction in mammalian cells"
2:25pm Dr. Martin Falcke
Hahn-Meitner Institute, Department of Theory
"On the role of fluctuations in intracellular calcium dynamics"
3:00pm Professor James Collins
Boston University, Biomedical Engineering
Co-Director, Center for Biodynamics
"Designer Gene Networks"
3:35pm Coffee Break
3:50pm Professor Dr. Thomas Hofer
Humboldt University, Institute of Biology, Department of Theoretical Biophysics
"Deterministic and stochastic models of cytokine memory in T helper lymphocytes"
4:25pm Professor Reinhart Heinrich
Humboldt University, Institute of Biology, Department of Theoretical Biophysics
"Mathematical modeling of metabolic and regulatory networks"


Saturday July 27, 2002

PATHWAY IDENTIFICATION AND ANALYSIS
Introductions by Robert Anderson, Boston University
9:00am Professor Scott Schaus
Boston University, Dept. of Chemistry
"A Chemical Genetic Approach to Understanding Kinase Activation and Function"
9:35am Katrin Hafez
Max Delbruck Center for Molecular Medicine, Bioinformatics, Berlin, Germany
"Intraparticle and interparticle distribution of lipoprotein components - an object-oriented modeling approach"
10:05am Professor Erwin Frey
Hahn-Meitner Institute, Department of Theory
"Actin Networks and Polymer Physics"
10:40am Coffee Break
11:00am Andreas Modler
Max Delbruck Center of Molecular Medicine, Department of Biopolymerphysics
"Nucleation versus coagulation ? parallel pathways for amyloid formation?"
GENE EXPRESSION AND FUNCTIONAL GENOMICS
Introductions by Joe Mellor, Boston University
11:30am Avi Spira
Senior Fellow in Pulmonary and Critical Care Medicine
Boston University School of Medicine
"Gene-Experssion Profiles of Smokers and Nonsmokers with Denocarcinoma of the lung"
12:00pm Lunch Break
1:30pm T.M. Murali
Research Associate Professor Boston University, Bioinformatics Program
"Distilling Gene Formulae from Gene Expression Data"
2:05pm Professor Erwin Stoschek
Technical University Dresden, Faculty of Informatics, 01062 Dresden, Germany
"Algorithmic generation of computer graphics, particularly of oral and animal patterns, mimicing aspects of gene expression"
2:40pm Peter Haverty
Boston University, Bioinformatics Graduate Program
"Cross Validation and Comparison of High-Density Oligonucleotide Arrays and EST-Based Expression Analysis"
3:10pm Closing Remarks
Prof. Charles DeLisi
Chair, Bioinformatics Graduate Program
Dean Emeritus, College of Engineering, Boston University